Ebola Battled By Robert Rowen MD With Ozone Therapy In Sierra Leone Update 12-14-14

Robert Rowen MD battles ebola with ozone therapy.

WHY OZONE FOR EBOLA AND OTHER VIRUSES, AS PROMISED
PLEASE, PLEASE READ IN FULL
(reposted due to problems with “share”. Those who have already read it, please “like” and share again as the whole original post text did not travel with the “share”)

I offered, and Mr. Roy challenged me, to provide information on why ozone should be considered for Ebola. With respect for Mr. Roy, though of significant value otherwise, much of what he has posted here is not directly relevant to human Ebola infection and ozone therapy.

Dr. Robins and I have had nearly 60 years combined experience with ozone treating a wide variety of viruses. That is not enough, as it is not published. And to demand that we provide a study on ozone and Ebola is totally unreasonable. How can we possibly do that absent assistance from those who gather up Ebola patients, carry them away in paddy wagons, and house them almost like criminals? So, as promised, I’ll give you the nuts and bolts of why ozone should quickly dispatch Ebola. You be the judge if it should be given a fair chance to save people with an otherwise 60% risk of death.

Numerous articles discuss the mechanism of viral entry into cells. That is a required step in the disease. If you can’t get in the door, you can’t rob a house.

Viruses, inclusive of Ebola, have a lipid envelope (see diagram attached) . On the lipid envelope there are critical molecules called glycoprotiens. The latter are so named because they are proteins with a sugar (glyco) molecule attached. They are NOT decorations!

The membrane/envelope is a critical structure for the virus. Alteration of it is published to damage its infectivity. One report says that targeting the lipid envelope is prime for drug research, but that the drugs are likely to be toxic. “Alterations of membrane lipid composition can block viral release and entry, and certain lipids act as fusion inhibitors, suggesting a potential as antiviral drugs……. Understanding the manifold roles of lipids in viral replication also led to the discovery of lipid-active compounds as potential antivirals, but current compounds largely lack specificity and are thus unacceptably toxic.”(1)

Mr. Roy, ozone directly attacks lipids (fats). The viral lipids “stolen” (see diagram) from the host cell (human) are susceptible to ozone. Ozone is not toxic at all to us because our oxygen breathing cells combust oxygen and are made for oxidative stresses. In fact, your own body actually makes ozone and other oxidants to kill invaders (Scripps Institute Research).(2) Viruses and bacterial pathogens have NO such defenses.

Now viruses, EBOLA included, need fully functional glycoproteins to enter cells. The “working” part of most proteins is “reduced” sulfhydryl groups (SH) called thiols. Proteins, inclusive of viral entry proteins, can be inactivated by “oxidizing” the reduced thiols to disulfides. SH + SH + O3 > S-S + H2O + O2. The alteration of SH to S-S by oxidation/ozone inactivates the protein. It’s like cutting off the “fingers” the virus uses to open the door and enter your cells. Ozone literally combusts the reduced thiols to harmless water and inactive oxidized S-S. I don’t expect you to believe me. So, let’s look at what the world literature has to say:

“Our studies have also allowed us to determine the disulfide-bond map of the Ebola glycoprotein and to propose that reduction of the disulfide bond between the two subunits of the Ebola glycoprotein complex, GP1 and GP2, is a CRITICAL [emphasis added] step in the entry of Ebola virus into cells.” (3)

“Many fusogenic glycoproteins of viruses which fuse with the plasma membrane, e.g. cytomegalovirus (CMV) (Compton et al., 1992), human immunodeficiency virus (HIV) (Freed & Martin, 1995 ; McClure et al., 1988) and paramyxovirus (Lamb, 1993), are rich in disulfide bonds and it is tempting to speculate on the role that disulfide bonds play during disassembly. Ryser et al. (1994) have recently suggested that HIV and its target cell engage in a thiol–disulfide interchange reaction and that reduction of critical disulfide bonds in viral glycoproteins may be the initial event that triggers the conformational changes required for HIV entry. In the present study we determined whether CMV contains free thiol groups that are essential for entry and infectivity”. [and in fact, CMV is totally dependent on free thiols for infectivity as they found].(4)

Mr. Roy, we have here the science that the glycoprotein redox status is CRITICAL for viral entry. We know that ozone and it’s blood reaction products oxidize free thiols to disulfides on contact (simple chemistry) and releases free energy. We know our cells can immediately repair this, and is part of ozone’s biochemical benefits on mammalian cells. (Our cells can reconvert S-S back to SH). We know that viruses CANNOT repair anything themselves. All they are are replicating machines, which require entry into cells to replicate. Take away their means for entry, and they are harmless, inclusive of EVERY virus. We know that ozone is safe. We know that ozone is 100x more effective a topical antimicrobial than is chlorine (5), currently used in Ebola centers. We know ozone has had millions of administrations in Europe, Asia, USA, Cuba and South America with a safety record far greater than aspirin.

So, Mr. Roy, if you or a relative developed Ebola, and you KNOW that you’ll have a 60% mortality rate, would you deny yourself or her ozone therapy knowing this information? What would you have to lose? And, if you would NOT deny yourself ozone therapy, then why on earth would you sustain the authorities denying it to infected doctors and others? I asked this on national television (National Encounter) in Sierra Leone to a government official. HE COULD NOT ANSWER! (His nod admitted that he’d want his mother to get ozone therapy).

I ask the same of all the health authorities, now, all over the world allegedly “battling” Ebola. This includes MSF (Doctors Without Borders), the WHO, the government ministers of Sierra Leone, and any official or professional reading this. Please stand up and tell me openly and honestly why ozone therapy does not deserve a CHANCE to save lives in a disease where the victim is LIKELY to die. Are you “battling” Ebola, or are you profiting from it? Does ozone therapy not deserve to be studied? I ask you all who read this to judge and make comments. I can take it!!!

Facebook Family, PLEASE SHARE THIS AND “LIKE” this page. Dr. Robins and I simply cannot do this without you. Please leave a comment. Demand news reporting of EVERYTHING on this site, talk show coverage, radio, etc. If this information goes “viral” as it should, perhaps we will see the action we need to save human beings, stop the orphaning, and end the worldwide fear of this dread malady. I told you it could be real simple. For those of you in Sierra Leone, please link this on every Ebola page out there. Your lives may depend on it. We already have one confirmed case of Ebola in a doctor (M’Briwa) apparently CURED with ozone, for less than 5 USD in materials!

Mr. Roy, you might not need the complexity of your posted materials to get to the bottom of this. Please read this post again and again. And, I kindly thank you for your interest.

PS I want everyone to remember that I am only a clinician. Why are the scientists and researchers unable to connect the above dots?

References (Facebook would not accept proper footnoting):
1. Cold Spring Harb Perspect Biol. 2011 Oct 1;3(10):a004820
2. PNAS | March 18, 2003 | vol. 100 | no. 6 | 3031-3034
3. David A Sanders Associate Professor of Biological Sciences Ph.D 1989 – University of California, Berkeley
4. Journal of General Virology (1999), 80, 2861–2865
5.Disinfection Using Chlorine Bleach December, 2011 / OSU Biological Safety / Environmental Health & Safety / 541-737-4557

Photo: WHY OZONE FOR EBOLA AND OTHER VIRUSES, AS PROMISED<br />
PLEASE, PLEASE READ IN FULL<br />
(reposted due to problems with "share". Those who have already read it, please "like" and share again as the whole original post text did not travel with the "share")</p>
<p>I offered, and Mr. Roy challenged me, to provide information on why ozone should be considered for Ebola. With respect for Mr. Roy, though of significant value otherwise, much of what he has posted here is not directly relevant to human Ebola infection and ozone therapy. </p>
<p>Dr. Robins and I have had nearly 60 years combined experience with ozone treating a wide variety of viruses. That is not enough, as it is not published. And to demand that we provide a study on ozone and Ebola is totally unreasonable. How can we possibly do that absent assistance from those who gather up Ebola patients, carry them away in paddy wagons, and house them almost like criminals? So, as promised, I’ll give you the nuts and bolts of why ozone should quickly dispatch Ebola. You be the judge if it should be given a fair chance to save people with an otherwise 60% risk of death.</p>
<p>Numerous articles discuss the mechanism of viral entry into cells. That is a required step in the disease. If you can’t get in the door, you can’t rob a house.</p>
<p>Viruses, inclusive of Ebola, have a lipid envelope (see diagram attached) . On the lipid envelope there are critical molecules called glycoprotiens. The latter are so named because they are proteins with a sugar (glyco) molecule attached. They are NOT decorations!</p>
<p>The membrane/envelope is a critical structure for the virus. Alteration of it is published to damage its infectivity. One report says that targeting the lipid envelope is prime for drug research, but that the drugs are likely to be toxic. "Alterations of membrane lipid composition can block viral release and entry, and certain lipids act as fusion inhibitors, suggesting a potential as antiviral drugs……. Understanding the manifold roles of lipids in viral replication also led to the discovery of lipid-active compounds as potential antivirals, but current compounds largely lack specificity and are thus unacceptably toxic."(1)</p>
<p>Mr. Roy, ozone directly attacks lipids (fats). The viral lipids "stolen" (see diagram) from the host cell (human) are susceptible to ozone. Ozone is not toxic at all to us because our oxygen breathing cells combust oxygen and are made for oxidative stresses. In fact, your own body actually makes ozone and other oxidants to kill invaders (Scripps Institute Research).(2) Viruses and bacterial pathogens have NO such defenses. </p>
<p>Now viruses, EBOLA included, need fully functional glycoproteins to enter cells. The “working” part of most proteins is “reduced” sulfhydryl groups (SH) called thiols. Proteins, inclusive of viral entry proteins, can be inactivated by “oxidizing” the reduced thiols to disulfides. SH + SH + O3 > S-S + H2O + O2. The alteration of SH to S-S by oxidation/ozone inactivates the protein. It's like cutting off the "fingers" the virus uses to open the door and enter your cells. Ozone literally combusts the reduced thiols to harmless water and inactive oxidized S-S. I don’t expect you to believe me. So, let’s look at what the world literature has to say: </p>
<p>“Our studies have also allowed us to determine the disulfide-bond map of the Ebola glycoprotein and to propose that reduction of the disulfide bond between the two subunits of the Ebola glycoprotein complex, GP1 and GP2, is a CRITICAL [emphasis added] step in the entry of Ebola virus into cells.” (3)</p>
<p>“Many fusogenic glycoproteins of viruses which fuse with the plasma membrane, e.g. cytomegalovirus (CMV) (Compton et al., 1992), human immunodeficiency virus (HIV) (Freed & Martin, 1995 ; McClure et al., 1988) and paramyxovirus (Lamb, 1993), are rich in disulfide bonds and it is tempting to speculate on the role that disulfide bonds play during disassembly. Ryser et al. (1994) have recently suggested that HIV and its target cell engage in a thiol–disulfide interchange reaction and that reduction of critical disulfide bonds in viral glycoproteins may be the initial event that triggers the conformational changes required for HIV entry. In the present study we determined whether CMV contains free thiol groups that are essential for entry and infectivity”. [and in fact, CMV is totally dependent on free thiols for infectivity as they found].(4)</p>
<p>Mr. Roy, we have here the science that the glycoprotein redox status is CRITICAL for viral entry. We know that ozone and it’s blood reaction products oxidize free thiols to disulfides on contact (simple chemistry) and releases free energy. We know our cells can immediately repair this, and is part of ozone’s biochemical benefits on mammalian cells. (Our cells can reconvert S-S back to SH). We know that viruses CANNOT repair anything themselves. All they are are replicating machines, which require entry into cells to replicate. Take away their means for entry, and they are harmless, inclusive of EVERY virus. We know that ozone is safe. We know that ozone is 100x more effective a topical antimicrobial than is chlorine (5), currently used in Ebola centers. We know ozone has had millions of administrations in Europe, Asia, USA, Cuba and South America with a safety record far greater than aspirin. </p>
<p>So, Mr. Roy, if you or a relative developed Ebola, and you KNOW that you’ll have a 60% mortality rate, would you deny yourself or her ozone therapy knowing this information? What would you have to lose? And, if you would NOT deny yourself ozone therapy, then why on earth would you sustain the authorities denying it to infected doctors and others? I asked this on national television (National Encounter) in Sierra Leone to a government official. HE COULD NOT ANSWER! (His nod admitted that he'd want his mother to get ozone therapy). </p>
<p>I ask the same of all the health authorities, now, all over the world allegedly “battling” Ebola. This includes MSF (Doctors Without Borders), the WHO, the government ministers of Sierra Leone, and any official or professional reading this. Please stand up and tell me openly and honestly why ozone therapy does not deserve a CHANCE to save lives in a disease where the victim is LIKELY to die. Are you “battling” Ebola, or are you profiting from it? Does ozone therapy not deserve to be studied? I ask you all who read this to judge and make comments. I can take it!!!</p>
<p>Facebook Family, PLEASE SHARE THIS AND “LIKE” this page. Dr. Robins and I simply cannot do this without you. Please leave a comment. Demand news reporting of EVERYTHING on this site, talk show coverage, radio, etc. If this information goes “viral” as it should, perhaps we will see the action we need to save human beings, stop the orphaning, and end the worldwide fear of this dread malady. I told you it could be real simple. For those of you in Sierra Leone, please link this on every Ebola page out there. Your lives may depend on it. We already have one confirmed case of Ebola in a doctor (M'Briwa) apparently CURED with ozone, for less than 5 USD in materials!</p>
<p>Mr. Roy, you might not need the complexity of your posted materials to get to the bottom of this. Please read this post again and again. And, I kindly thank you for your interest. </p>
<p>PS I want everyone to remember that I am only a clinician. Why are the scientists and researchers unable to connect the above dots?</p>
<p>References (Facebook would not accept proper footnoting):<br />
1. Cold Spring Harb Perspect Biol. 2011 Oct 1;3(10):a004820<br />
2. PNAS | March 18, 2003 | vol. 100 | no. 6 | 3031-3034<br />
3. David A Sanders Associate Professor of Biological Sciences Ph.D 1989 - University of California, Berkeley<br />
4. Journal of General Virology (1999), 80, 2861–2865<br />
5.Disinfection Using Chlorine Bleach December, 2011 / OSU Biological Safety / Environmental Health & Safety / 541-737-4557

Your medical servant,
Robert Rowen MD

https://www.facebook.com/DrRobertJRowen

[1] 2200 County Center Dr. Ste C, Santa Rosa, CA 95403  707-578-7787  drrowen@att.net

[2] 200 W. 57th St  #807, New York, NY 10019  516-967-1009  drhowardrobins@gmail.com